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Pathophysiology Of Colorectal Cancer Pdf​

Pathophysiology of Colon Cancer | PDF - Scribd

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Attribution Non-Commercial (BY-NC) Available Formats. Download as DOC, PDF, TXT or read online from Scribd. Flag for inappropriate content. Download now. Save Save Pathophysiology of Colon Cancer (1) For Later. 45% (11) 45% found this document useful (11 votes) 13K views 3 pages.

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Colon Cancer Pathophysiology PDF | PDF | Colorectal Cancer ...

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Colon cancer pathophysiology pdf Colorectal cancer is the third leading cause of cancer-related death in. Current knowledge of molecular pathogenesis in common hereditary. colon cancer pathophysiology pdf A review of the pathophysiology, clinical presentation, and diagnosis of colon cancer is important and timely. This field is changing

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"Pathophysiology of Colorectal Cancer" by Jessica Okey

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Colorectal cancer (CRC) is a slow developing preventable cancer that occurs after colon or rectal polyps undergo abnormal cellular changes. CRC is a very common cancer but can be preventable if screenings are completed as recommended.

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Pathophysiology, clinical presentation, and management of ...

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Pathophysiology, clinical presentation, and management of colon cancer Colon cancer is believed to arise from two types of precursor polyps via two distinct pathways: conventional adenomas by the conventional adenoma-to-carcinoma sequence and serrated adenomas according to the serrated adenoma-to-carcinoma theory.

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Colorectal Cancer, Pathophysiology of Colorectal Cancer ...

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Pathophysiology of Colorectal Cancer CRC results from a stepwise accumulation of genetic defects and clonal proliferation of mutated colonic epithelial cells in an adenomacarcinoma transformation sequence of normal colonic mucosa, a protuberant growth known as polyp or adenoma (Fig. 1), and ultimately adenocarcinoma [5].

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Colorectal Cancer - Pathophysiology | Gastrointestinal Cancer

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Left-sided colorectal cancer (LCRC) occurs in the distal colorectum and consists of cancers of the descending and sigmoid colon and the rectum. 2. Tumors of the proximal colon tend to be larger, have a higher TNM-stage, and have increased frequency of vascular invasion than LCRC.

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COLORECTAL CANCER - ncbi.nlm.nih.gov

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The main causes of cancer-related mortality have also changed, attributable to alterations in disease incidence, introduction of screening programmes and therapeutic improvements. Colorectal cancer was rather rare in 1950, but has become a predominant cancer in Western countries, now accounting for approximately 10% of cancer-related mortality.

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PATHOPHYSIOLOGY OF COLORECTAL CANCER.pdf - PATHOPHYSIOLOGY ...

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View PATHOPHYSIOLOGY OF COLORECTAL CANCER.pdf from NURSING 123 at Pines City Colleges, Baguio City. PATHOPHYSIOLOGY OF COLORECTAL CANCER Predisposing Factors: Colorectal polyps Family

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Pathophysiology of Colorectal Cancer.pdf - Otterbein ...

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Image 1 (Buccafusca et al., 2019) Why choose Colorectal Cancer? The topic CRC was chosen because the author is employed in a gastrointestinal endoscopy unit and is a part of a team that completes routine colorectal cancer screenings. The author would like to gain a deeper understanding of the pathophysiology of this disease.

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(PDF) Colorectal cancer - ResearchGate

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Colorectal cancer had a low incidence several decades ago. However, it has become a predominant cancer and now accounts for approximately 10% of cancer-related mortality in western countries.

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Cancer: etiology, pathophysiology, types, diagnosis and ...

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Cancer pathophysiology. Regardless of difference in types of cancer histologically and physiologically, there is existence of a common pathophysiological process of malignant tumors or cancer development in the organism. The commonly accepted basis of the pathogenesis of cancer is the damage to the genetic

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Pathophysiology, Clinical Presentation, and Management of ...

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Colorectal cancer afflicts approximately 150,000 Americans annually, approximately one third of whom die .It afflicts approximately 250,000 annually in Europe and approximately 1 million people worldwide .A review of the pathophysiology, clinical presentation, and diagnosis of colon cancer is important and timely.

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Colorectal cancer - Wikipedia

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Colorectal cancer is a disease originating from the epithelial cells lining the colon or rectum of the gastrointestinal tract, most frequently as a result of mutations in the Wnt signaling pathway that increase signaling activity. The mutations can be inherited or acquired, and most probably occur in the intestinal crypt stem cell.

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Epidemiology of colorectal cancer

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Introduction. The term colorectal cancer refers to a slowly developing cancer that begins as a tumor or tissue growth on the inner lining of the rectum or colon [].If this abnormal growth, known as a polyp, eventually becomes cancerous, it can form a tumor on the wall of the rectum or colon, and subsequently grow into blood vessels or lymph vessels, increasing the chance of metastasis to other ...

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Colorectal cancer: Etiology and pathophysiology ...

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Much has been learned about the development of colorectal cancer. Risk factors appear to include genetic predisposition, nonspecific injury, precursor conditions such as inflammatory bowel disease and adenomatous polyps, and diet. Epidemiologic studies strongly implicate the Western diet (high fat, low fiber) in development of colorectal cancer ...

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(PDF) Colorectal cancer: a review - ResearchGate

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Colorectal cancer (CCR) is the third most common cancer worldwide in men and women, the seco nd largest cause of. death related to cancer, and the main cause of death in gastrointestinal cancer ...

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Colon cancer - Symptoms and causes - Mayo Clinic

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If colon cancer develops, many treatments are available to help control it, including surgery, radiation therapy and drug treatments, such as chemotherapy, targeted therapy and immunotherapy. Colon cancer is sometimes called colorectal cancer, which is a term that combines colon cancer and rectal cancer, which begins in the rectum.

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Gastric Cancer - Pathophysiology | Gastrointestinal Cancer

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Pathophysiology of gasteric cancer. Approximately 95% of stomach tumors are epithelial in origin and are classified as adenocarcinomas. 1 Gastric cancers are most often found in the gastric cardia (31%), followed by the antrum (26%) and the body of the stomach (14%). Linitis plastica, a type of adenocarcinoma that diffusely infiltrates the stomach wall, accounts for the remaining 10% of cases. 2

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What is the pathophysiology of colon cancer?

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Genetically, colorectal cancer represents a complex disease, and genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma.

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What is the pathophysiology of rectal cancer?

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[Guideline] Levin B, Lieberman DA, McFarland B, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American ...

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Fix Amazon Login Account Problems on Your Own Through The Following Tips

Many folks have difficulty signing out of their Amazon accounts. If so, you may have a problem with your Amazon account. Amazon may lock your account due to a privacy problem, so don't be alarmed. In addition, to fix Amazon Login account problems. It is possible to fix these problems with a resolution. You may be able to fix the problem yourself rather than relying on Amazon. Here are, we'll explain Solutions for Amazon Login Account Problems. Why is Amazon Preventing from Logging In? Amazon refuses to accept your password when you try to log in regularly. Maybe you're using the wrong credentials to get in. There are several things you can take to prevent your account from being hacked in the first place to fix amazon login account problems. Forgot Your Password? Use the proper email address and password to log into your Amazon account. An error occurs if an email address has a single incorrect format at the login moment. Mobile Phone Number Keep in mind that if you set up an account using your mobile phone number, make sure you sign in using the same phone number and password you used to set up your account to fix amazon login account problems. Password The CAPS lock and NUM lock on your keyboard should be checked once you've entered your password. Both 'PASSWORD' and 'PASSWORD' are interpreted when you enter them into the system. Problem with Logging into your Amazon Account Most of the time, it's a simple case of forgetting your password or inputting the wrong one. If your username and password don't match, you can reset your password or use OTP to log in. To regain access to your Amazon account, follow these steps. Step 1: As a general rule, you cannot log in because your password and login ID do not match.  Step 2: Activate the password helper. Step 3: Once you've entered the email or phone number associated with your Amazon account, click on the Continue button. Step 4: You'll get an OTP through email or text message now. Step 5: This one-time password must be entered and tapped on to proceed. Step 6: Creating a new password and remembering it for future use is now possible.  Step 7: You can now log in to your Amazon account successfully. Make A Clean Sweep of Your Browser's Cache Files The first step is to go to your browser's settings and then access the application menu by clicking on three horizontal icon bars to fix amazon login account problems. Open the 'settings' menu next. Go to your account's 'privacy and security section. Remember that if Firefox is not selected, all erase cookies and site data will not be selected in the data preferences. Check All History Preferences Except for Firefox History Hopefully, your browser settings will positively impact your situation within a reasonable amount of time. Other solutions to amazon login account issues include: In addition, you must keep your application up to date regularly. If your application has a bug, it will fix itself with a single update. Restarting Your Device In the case of Amazon account login issues, a brief restart works as well. If you're trying to log in to your Amazon account via a browser, this advice is highly recommended to fix amazon login account problems. You can access your Amazon account by clicking on the link that lets you circumvent the login issue. For mobile devices running iOS or Android, there are two links to choose to fix amazon login account problems. Amazon Continually Asking Me to Log-In It happens a lot on Amazon.com, and you may not be logged out. You will be prompted to verify your identification after logging back into your account for the second time. It is done so that your account is better protected. It means that you shouldn't keep the signed me on Amazon at all times. It's not a good idea because it's not secure, and anyone may access your account. So, it's unnecessary to keep the account inactive. However, you can leave your Amazon account open to fix amazon login account problems. Problem with Your Amazon Account's Security Amazon accounts can be locked for no apparent reason at all. As a result, it's important to take a moment to consider this key factor. Depending on whether or not the payment card verification is successful The use of two or more IP addresses in several places. Information that isn't correct Orders from a new account have increased significantly. Conclusion Amazon account login issues can be frustrating, and this article will help you figure them out. Using the browser settings process and being aware of the incorrect login method is also helpful in resolving this issue. That raises a slew of fixed amazon login account problems. You don't have to worry when it comes to managing and logging into your account.
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How to Log in to Amazon without Verification Code?

As a result of two-factor authentication, if your phone is stolen or lost, you may also lose the ability to log in to online sites like Amazon. The good news is that we've discovered a workaround for those of you who are having trouble logging in to log in to Amazon without verification code. Login Amazon Account without Verification Code A few alternative techniques to get into your Amazon account will be discussed before we get into the real account recovery process, which we'll cover in detail below. To be precise, there are two. Follow these procedures to log in to Amazon without a verification code. Your cursor over your name on the Amazon desktop site. Click on Hello, Your Name, and then Your Account. Click on Login & security. For two-step verification (2SV) settings, click Edit. Click Disable Two-Step Verification. Text or Call for An OTP If you lose your phone, you also lose access to the SIM card. To switch to a new SIM card, call your wireless service provider and request that your old one be disabled. A different phone number, such as one belonging to a member of your immediate family, may have been provided for you to use that number to log in to amazon without a verification code. Click on Didn’t Get The OTP The screen that appears when you sign up for an Amazon account and input your ID and password is called the Amazon 2FA page to log in to Amazon without Verification Code. Re-Enter Your Sign-in Credentials Amazon will display the last three digits of the backup phone number if added to the list. Using this number is as simple as logging in with a one-time password (OTP).  Step 1: Click on Send OTP and then Text or Call to send the code. Step 2: Enter the OTP you received through text or phone call to the backup phone number and click Sign In. You're now logged in. Step 3: Login and security are available under Amazon Account settings, which you can access at a later time. Two-factor authentication settings may require a new login.  Step 4: It's now time to update your authentication phone number or disable Two-Step Verification until you have a new phone and SIM card set up.  Step 5: To do this, click the Edit button below the Two-Step Verification settings. Locate A Reputable Device Don't ask for codes on this device; have a checkbox next to it when you connect to your Amazon account. If you've previously activated this option on another device, you won't have to enter the Authentication to log in to Amazon without Verification Code. Depending on where you work, it could be on a desktop or a laptop. It's well worth a look.  Recovering A Deleted Amazon Account Amazon's account recovery procedure is surprisingly simple. Using your Amazon password, log in to the account recovery page to provide verification information, such as a driver's license or voter ID. To submit the document, you can choose to upload it as a document, a PDF, or an image to log in to Amazon without Verification Code.  Make Your Account Future-Proof There are several ways to regain access to your account, but none of them are foolproof. A trusted device may not be available, or your account recovery process may be rejected. There are no promises.  Authentication from Two Phones In contrast to many other sites, Amazon allows you to add numerous authentication apps simultaneously, and all of the codes will function. As a result, using two phones for Authentication will make to login amazon without a verification code on another device considerably simpler. Step 1: Open Amazon. Select Account & Lists. Pick Your Account from the drop-down menu to add Authentication. Step 2: To access the security settings, select Login & Security and input your Amazon account password. Step 3: Complete the two-step verification process and click on the Edit button next to Two-Step Verification Settings to make changes. Step 4: Add a new app next to the authenticator app by clicking on Add new app. Step 5: Authentication is now complete.  Step 6: To verify, enter the one-time password (OTP) created by the app. Step 7: This method works with any phone in your family, including those with whom you have a shared Amazon Prime membership Assemble Extra Phone Number Adding numerous phone numbers for Authentication is just like adding a new authenticator app. 1: When you arrive at the Two-Step Verification page, select add a new phone. 2: Continue by entering a new phone number here. 3: Now, when you check-in, you'll also be able to utilize this phone number to receive a text or voicemail. Conclusion If you only require a few pieces of paperwork to verify your account, it may not always be successful. Because of this, it is a good idea to enable a secondary authentication device and a trusted phone number. Make sure this doesn't happen again by taking the required precautions to log in to Amazon without a verification code.
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10 Straightforward Ways to Stay Safe from Cyber Attacks

A cyber-attack is purposeful double-dealing of your frameworks as well as your organization. Cyber-attacks utilize malevolent code to think twice about PC, rationale, or information and take hole or hold your information prisoner. Cyber-attack counteraction is fundamental for each business and association. Here are a few instances of cyber-attacks: Wholesale fraud, misrepresentation, blackmail  Malware, phishing, spamming, parodying, spyware, trojans, and infections  Taken equipment, like workstations or cell phones  Refusal of administration and circulated disavowal of administration assaults  Break of access  Secret key sniffing  Framework invasion  Site mutilation  Private and public Web program takes advantage of  Texting misuse  Protected innovation (IP) burglary or unapproved access  Today, Loginnote will give you 10 Simple Tricks that you can stay safe from Cyber Attacks.  1. Train Your Staff  Quite possibly, the most well-known way digital hoodlums gain admittance to your information is through your representatives. They'll send false messages imitating somebody in your association and will either request individual subtleties or for admittance to certain records. Connections regularly appear authentic to an undeveloped eye, and it's not difficult to fall into the snare. It is the reason representative mindfulness is indispensable.  Look at joins before clicking the  Browse email addresses from the got email.  Utilize presence of mind before sending touchy data. On the off chance that a solicitation appears odd, it most likely is. It's smarter to  check through a call with the individual being referred to before auctioning the "demand."  2. Keep Your Programming and Frameworks Completely Modern Regular cyber-attacks happen because your frameworks or programming aren't completely state-of-the-art, leaving shortcomings. Programmers exploit these shortcomings, so cybercriminals exploit these shortcomings to get sufficiently close to your organization. When they are in – it's regularly past the point where it is possible to make a precaution move. To check this current savvy, put resources into fixing the board framework that will deal with all product and framework refreshes, keeping your framework versatile and state-of-the-art.  3. Guarantee Endpoint Protection Endpoint assurance secures networks that are remotely crossed over to gadgets. Cell phones, tablets, and PCs associated with corporate organizations give access to ways to security dangers. These ways need to be ensured with explicit endpoint security programming.  4. Introduce A Firewall There are countless various sorts of modern information breaks, and new ones surface each day and even make rebounds. Putting your organization behind a firewall is one of the best ways of protecting yourself from any cyber-attack. A firewall framework will hinder any beast power assaults made on your organization and frameworks before it can do any harm, something we can assist you with.  5. Reinforcement of Your Information  In case of a debacle (regularly a cyber-attack), you should have your information reared up to keep away from genuine vacation, loss of information, and genuine monetary misfortune.  6. Control Admittance to Your Frameworks In all honesty, one of the assaults you can get on your frameworks can be physical; having command over who can access your organization is outrageously significant. Someone can stroll into your office or endeavor and plug in a USB key containing tainted documents into one of your PCs, permitting them admittance to your whole organization or contaminating it.  7. Wifi Security Who doesn't have a wifi-empowered gadget in 2020? Furthermore, that is, by and large, the risk. Any gadget can get contaminated by interfacing with an organization; assuming this tainted gadget is associated with your business network whole framework is in genuine danger.  Getting your wifi organizations and concealing them is perhaps the most secure thing you can accomplish for your frameworks. With growing more and more regularly, many gadgets can interface with your organization and compromise you.  8. Representative Individual Records A few clients interfacing under equivalent qualifications can endanger your business.  Having separate logins for each staff part will assist you with lessening the number of assault fronts. Clients sign in once every day and utilize their own logins arrangement. More noteworthy security isn't the main advantage; you'll likewise get improved ease of use.  9. Access Management One of the dangers of being an entrepreneur and having workers introduce programming on business-claimed gadgets that could think twice about frameworks. Having overseen administrator privileges and impeding your staff from introducing or, in any event, getting to specific information on your organization is helpful to your security. It's your business; ensure it!  10. Passwords Having a similar secret key arrangement for everything can be risky. When a programmer sorts out your secret word, they presently have admittance to everything in your framework and any application you use. Having various passwords arrangement for each application you use is a genuine advantage to your security, and transforming them will maintain  Conclusion It tends to be hard to tell where to start regarding shielding your business from digital wrongdoing and cyber-attacks. There's so much data out there that it can become overpowering, particularly when the information is clashing. You want an answer that is appropriate for your business and your representatives. Reach out to us today for a no-commitment network protection appraisal. We can help launch your excursion to become secure.
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How to Access Your Wi-Fi Router's Settings?

Your router saves the settings for your home Wi-Fi network. If you want to change anything on your network, then you have to log into your router's software that is known as firmware. In this way, you have an option to rename your network, change the password, adjust the security level, generate a guest network, as well as set up or alter a variety of other options. Here we will discuss how can you first get into your router to make these kinds of changes?  The process for logging into your router must be the same as you use your internet provider's router or you bought your router. It must be the same as you use a dedicated router or a combination modem/router supplied by your internet provider as well. Find the Router's IP Address You log into your router's firmware through a browser. Any browser will find it for you. There you will type the IP address of your router at the address bar. However, that's not always the case, that's why first you should confirm the address of your router. Suppose you want to find your router's IP address, type "cmd" in the search window. Click on the Enter button to open the command prompt. Then type ipconfig in the command prompt. Press Enter to run the command. Furthermore, Scroll until you a setting for Default Gateway appear under Ethernet or Wi-Fi. That is your router, and the number next to it is your router's IP address. Now type the IP address of your router in the address field of your browser. Then press Enter hand to hand. Username and Password You will be asked to enter a username and password to access your router's firmware. It could be either the default username and password for your router.  Otherwise, a unique username and password would be generated by you when you set up the router.  If you generated your username and password, start login with these credentials now to see your router's firmware settings. In case, you don't remember your login information, or you never changed these credentials from the unit's default, the process may become a little more complicated.   Password Recovery Features Few routers provide a password-recovery feature. If it is true of your router, this option would have appeared if you enter the wrong username and password several numbers of times. On the other hand, the window will ask for your router's serial number that you can easily find on the bottom or side of the router. Most of the routers use a default username of admin and a default password if you never changed the router's login to start with. You can try these steps to see if they work or not. Else, the best option is to do a web search to get the default username and password of the brand name of your router. There is also an option to search a database for your particular router model's default login personal information. Once you get the correct login credentials, you can try logging into your router now.  In case you still are not able to log into your router's firmware, it's the right time to reset the device to revert all settings to their defaults. Furthermore, you will usually get a mini reset button on your router. Use a pointed object such as a pen or paper clip, for pushing in and hold the reset button for around a few seconds. I this way, you will now be able to log into your router by using the default username and password. Change Router Settings Once you get access to the router's firmware, you are allowed to change whatever elements required to be changed. It includes network name and password, or the security level too. Parental controls can be implemented from the router's main screen, as well as a guest network can be generated.  Furthermore, attached devices can be managed as well. Do remember to apply any changes before you move onto the next screen. Documentation with built-in help must be available to assist you. You will get help with these settings if you are not sure how to set them. The latest or newest routers also have setup wizards that can take care of a few of this labor for you.  Change Router Login The better option is that change your router's username and password from their default values. It will efficiently secure your router so only you can access the firmware. You can change both the username and password with some routers. However, in other routers, you are allowed to change the password only, but the username is somehow stuck as admin. Look for an option while changing the password that is formerly available under the Administration tab. Furthermore, the screen will probably ask for your current router password. When you enter that, it will ask you to enter a new password. Keep remembering the general recommendations to create a secure password.
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